While in the process of raising my thyroid levels (my tsh was 21) I had to have a root canal. My dentist prescribed Hydrocodone to help reduce my pain the night before my scheduled procedure. I hadn't had any pain reliever other than over the counter drugs prior to this. About one hour after taking the hydrocodone my heart rate was slowing down to 56 bpm and my blood pressure (which is normally low) skyrocked to 220/160. I felt total panic and couldn't calm down. Even after having my root canal the next day, I felt like I was having an adrenalin rush for the next two days. Has anyone else ever had a reaction like this?