Hi berryk,
The answer really depends on just a few factors: what sort of system are you trying to protect, what level of protection do you need, and what it your budget?
For instance, if you're using a desktop computer at home, using it just to play games and surf the web, and your budget for virus protection is pretty small, then your AV choice would be vastly different from someone who uses a laptop strictly for work and will pay whatever it costs to protect their info.
Feel free to email me with more details so that I can offer specific help or of course, you can just reply to this post.
Thanks for your question!