cybercat,
It sounds like those Dr.s are staying on top of your son's situation and are fine tuning the diagnosis, to provide best possible treatment. I also like seeing Dr.s confer with other Dr.s to get the best input in putting together the full picture for what is needed.
They may see the possibility that there is still some recovery from the injuries taking place and is why some of the treatments may not need to be permanent but follow up retesting will reveal this if it's the case. Even if they are permanent, he can live a full, normal life with ongoing treatment.
I've seen the "isolated" term reported by patients as being the wording used on their lab results revealing Central Hypothyroidism and I believe it is just a little more descriptive but means basically the same thing. Central hypothyroidism itself is rare, I believe affecting less than 1% of the population. Others may have more input on the Central Hypo subject, my search and research is limited in that area.
Keep updating us when you can and we continue to wish you the very best and know your son will see great days ahead.