There are definitely some that work! I think you have to divide products into 2 groups. Some make your skin look and feel better, but don't really improve the quality of your skin. I'm not knocking them. Sometimes, even when you're working on "remodelling " your skin, you want to use something that improves the way it looks RIGHT NOW!
Personally, I like products with a high concentration of actives. They've really changed my skin so much. It's also the case that research is giving us so many great new active ingredients - many of them also natural ones! Case in point: tamarind seed extract. It's worth seeking out products with this ingredient because it's honestly awesome. It also seems to somehow regulate your skin. I may have mentioned bellapelleskincare.com - they make this all-in-1 firming elixir. Although the ingredients looked fantastic, I didn't think I'd be able to use the stuff because I have oily skin, but this stuff worked beautifully. When I asked them about it, they attributed it to the "regulating" quality of the tamarind seed extract.
Both this and their eye cream are definitely worth checking out though.