I have found the following helpful: Ultram, hydrocodone (when pain is especially bad and when traveling), Flexiril. A vegetarian diet has made a significant difference, as well as yoga, stretching, use of heat---hot tub soaks or lavender body wraps. Just recently I have begun treatment by a massage therapist who is first using cranio-sacrum therapy that is working very well. Topamax has eliminated the cluster/migraine syndrome, and I take Fioricet for the muscle tension headaches in the back of the head. At bedtime I take Topamax, Klonopin, Flexiril, Ultram, and Melatonin and I usuallly sleep fine. I try to maintain this regimen on a regular basis at minimal doses to keep pain under control and adjust dosage as needed. A positive attitude plus plenty of rest and not over doing it is also important.