Low-carb, low-fat diets do not work, and splenda does have bad side effects. Your body needs fats,(the right kind like what is found in avocados and olives), carbs, fiber, and protein in the right combinations and quantities. Chemical additives and the wrong foods (like highly processed foods and empty calories) are causing your body to turn on itself.
A natural whole food diet rich in whole, fresh fruits and vegetables combined with lots of fiber to slow down carbs turning to sugar in your blood is best.
Dr. Mark Hyman's
Ultra-Metabolism Book is the best I've seen on whole body health. It comes complete with foods to avoid, foods to eat, menus, recipes, and explanations. This diet will work for diabetes, food allergies, and to lose weight. While I say diet, it is more of a life-style change. While I had to adjust shopping for food and cooking, it was well worth it.
My triglycerides level was 479 and I've been able to reduce it down to normal levels just through my diet in 2 months. I've not been hungry at all and I feel better than I have in 20 years!