Hi Sara,
Large quilts are tough to handle on a small arm machine. You will need a walking foot for straight quilting. If your machine allows you to drop the feed dogs, you can do free motion quilting using a darning foot.
I feel like I'm fighting with a quilt when machine quilting. To alleviate the stress of handling a large bulky quilt, I prefer the Quilt-As-You-Go technique. Here is an excellent tutorial that will help you with this technique:
http://www.acornhillquilts.com/asyougo.htmI hope this helps and good luck with your quilting!