I support our local Animal Services volunteer group. They are very active on Facebook and work tirelessly to get dogs and cats adopted, rescued and fostered. They use the money to fun foster programs, education, spay and neutering and give money to rescue groups so various pets can go into rescue, rather than being euthanized. I used to support the local branch of the SPCA until I got involved in the animal services group.
I sell Avon and have an ongoing fundraiser where I donate 10% of purchases to the group.
I like supporting a very local group because I know where all the money goes and how it is spent.