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#227987 01/23/06 10:54 PM
Joined: Jan 2006
Posts: 137
Jellyfish
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Jellyfish
Joined: Jan 2006
Posts: 137
I'd like to know what issues are important to you, so I can try to address them. Feel free to post any topic. We need to work together to make tomorrow brighter for everyone.


A. Maria Hester, M.D.
Gynecology and Geriatrics Editor
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Joined: Oct 2003
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Info about treating the genetic blood disease hemochromatosis.

Over the Christmas holidays I found out 3 of my 1st cousins are being treated with phlebotomies. Their mothers are my father's 2 sisters. I have had a first round of blood work and I appear to have a mild case. A 4th cousin tested does not carry the gene.

Joined: Jan 2006
Posts: 137
Jellyfish
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Jellyfish
Joined: Jan 2006
Posts: 137
[color:"red"] Hereditary Hemochromatosis (HH) [/color] is a disorder of iron metabolism by the body. Basically, in this disorder there is an increase in iron absorption from the gut with subsequent deposition of this iron in tissues.

It is relatively common, with a reported incidence of close to 1 in 250 persons of Northern European descent. Fortunately, recent studies have shown that only 50% of those who have received a gene for the major mutation in HH [color:"red"] from both parents [/color] actually express clinical evidence of iron overload, and less than 10% develop tissue damage from excessive accumulation of iron.

Cecil's Textbook of Medicine lists four stages of HH:
1. Those who are geneticaly predisposed, but have no clinical abnormality
2. Those who have iron overload, but no symptoms
3. Those with iron overload with mild or early symptoms
4. Those with iron overload and organ damage

Even in those who do have clinical evidence of the disease, the treatment is simple (phlebotomy). Your doctor can tell you where you lie in the spectrum and what treatment (if any) needs to be given.

I hope this helps.


A. Maria Hester, M.D.
Gynecology and Geriatrics Editor
Power to the Patient!
BellaOnline ALERT: Raw URLs are not allowed in these forums for security reasons. Please use UBB code. If you don't know how to do UBB code just post here for help - we will help out!
Joined: Oct 2003
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Stone Age Human
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Thank you Dr. Maria!

Joined: Jan 2006
Posts: 137
Jellyfish
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Jellyfish
Joined: Jan 2006
Posts: 137
My pleasure.


A. Maria Hester, M.D.
Gynecology and Geriatrics Editor
Power to the Patient!
BellaOnline ALERT: Raw URLs are not allowed in these forums for security reasons. Please use UBB code. If you don't know how to do UBB code just post here for help - we will help out!

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