Sophia Brahe was born September 22, 1556 at Knudstrup, Sweden (which was at the time was still Danish). She was the younger sister of Tycho Brahe
. Coming from a noble family, both were ostracized for their scientific pursuits which were deemed inappropriate, especially for a noblewomen.
Sophia was a horticulturalist, but also educated in classical literature and chemistry. She was self-educated in astronomy, and frequently assisted her brother with his astronomical observations at his observatory Uraniborg. On one occasion she helped with the observations Tycho used to compute the total lunar eclipse of 8 December 1573.