Bipolar disorder runs strongly in my family. It has turned my family inside out on more than one occasion. The worst afflicted was my brother. He didn't like his meds because he liked the up sides but he self medicated with drugs and alcohol. I listened to him attempt to commit suicide over a police scanner. I was a reporter, it just happened to be my brother. Other family members suffer at a lesser degree. One in particular won't or can't admit they need help, and it hurts me greatly.
My brother is no longer with us, mostly on account of a national mental health system that is horribly broken.