One of the worst places that I've been seasick is in the Santa Barbara channel or along the coast of Santa Barbara. Especially on days when the swells run gently, almost parallel, to shore. I've been sick for 24 miles on a kayak trip one time, and I made a mess on a diving boat one time.

Actually, nowadays, I am prone to all types of motion sickness, from car to plane to diving, to water craft.

What works best for me, and doesn't make me sleepy is Meclizine (Bonine). What works well for you?